ARS2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | ARS2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted: zebrafish, X. laevis, bovine, orangutan) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-ARS2 antibody, affinity purified. Arsenate resistance protein 2 (ARS2) acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. ARS2 contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. ARS2 does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, it is necessary and sufficient to promote neural stem cell self-renewa and does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BXP5]. |
| Immunogen | Between 1 and 50 |
| Other Names | serrate; serrate RNA effector molecule homolog; ASR2; arsenite-resistance protein 2; arsenate resistance protein ARS2; ARS2; arsenate resistance protein 2; arsenite resistance protein |
| Gene, Accession # | Accession: NP_056992.4, Gene ID: 51593, UniProt: Q9BXP5 |
| Catalog # | A304-550A-T |
| Price | $121 |
| Order / More Info | ARS2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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