RAN Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-RAN antibody, protein, ELISA kits.
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| Antigenic Specificity | RAN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted: rat, X. laevis, chicken, bovine, dog, orangutan) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-RAN antibody, affinity purified. RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor [taken from NCBI Entrez Gene (Gene ID: 5901)]. |
| Immunogen | Between 166 and C-terminus |
| Other Names | OK/SW-cl.81; TC4; ras-related nuclear protein; RanGTPase; member RAS oncogene family; GTP-binding nuclear protein Ran; GTPase Ran; Gsp1; ARA24; androgen receptor-associated protein 24; ras-like protein TC4; guanosine triphosphatase Ran |
| Gene, Accession # | Accession: NP_006316.1, Gene ID: 5901, UniProt: P62826 |
| Catalog # | A304-297A-T |
| Price | $121 |
| Order / More Info | RAN Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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