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Antigenic Specificity | FAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-FAS antibody, affinity purified. Tumor necrosis factor receptor superfamily member 6, FAS, functions as the receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated FAS receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) which mediate apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P25445]. |
Immunogen | Between 285 and C-terminus |
Other Names | tumor necrosis factor receptor superfamily member 6; Fas AMA; FAS1; FASLG receptor; FASTM; mutant tumor necrosis receptor superfamily member 6; TNFRSF6; tumor necrosis factor receptor superfamily, member 6; apoptosis signaling receptor FAS; Fas (TNF receptor superfamily, member 6); TNF receptor superfamily member 6; Apo-1 antigen; APT1; CD95 antigen; APO-1; APO-1 cell surface antigen; apoptosis antigen 1; apoptosis-mediating surface antigen FAS; ALPS1A; CD antigen CD95; CD95 |
Gene, Accession # | Accession: NP_000034.1, Gene ID: 355, UniProt: P25445 |
Catalog # | A302-858A |
Price | $433 |
Order / More Info | FAS Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |