Edit |   |
---|---|
Antigenic Specificity | CAV1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: mouse, rat, sheep, bovine, horse, rabbit, pig, cat, orangutan, gorilla, chimpanzee |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CAV1 antibody, affinity purified. CAV1 acts as a scaffolding protein within caveolar membranes and forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. CAV1 also mediates the recruitment of CAVIN proteins to the caveolae and interacts directly with G-protein alpha subunits and can functionally regulate their activity. CAV1 is also thought to be involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, as its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q03135]. |
Immunogen | Between 1 and 50 |
Other Names | VIP21; PPH3; MSTP085; LCCNS; CGL3; cell growth-inhibiting protein 32; caveolin-1; BSCL3; caveolin 1, caveolae protein, 22kDa |
Gene, Accession # | Accession: NP_001744.2, Gene ID: 857, UniProt: Q03135 |
Catalog # | A305-901A |
Price | $433 |
Order / More Info | CAV1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |