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Antigenic Specificity | A20 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-A20 antibody, affinity purified. Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21580]. |
Immunogen | Between 550 and 600 |
Other Names | TNFA1P2; tumor necrosis factor, alpha induced protein 3; zinc finger protein A20; tumor necrosis factor inducible protein A20; tumor necrosis factor alpha-induced protein 3; A20; putative DNA-binding protein A20; OTUD7C; OTU domain-containing protein 7C; AISBL; TNF alpha-induced protein 3 |
Gene, Accession # | Accession: NP_006281.1, Gene ID: 7128, UniProt: P21580 |
Catalog # | A302-633A-T |
Price | $121 |
Order / More Info | A20 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |