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Antigenic Specificity | Toca-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Toca-1 antibody, affinity purified. Toca-1 is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Toca-1 also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T0N5]. |
Immunogen | Between 450 and 500 |
Other Names | formin-binding protein 1-like; TOCA1; toca-1; transducer of Cdc42-dependent actin assembly 1; transducer of Cdc42-dependent actin assembly protein 1; C1orf39 |
Gene, Accession # | Accession: NP_060207.2, Gene ID: 54874, UniProt: Q5T0N5 |
Catalog # | A303-470A-T |
Price | $121 |
Order / More Info | Toca-1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |