HLA-DR Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | HLA-DR |
| Clone | LN3 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 µl (50+ tests) |
| Concentration | 50 µg/ml |
| Applications | WB, IHC, ICC, IHC-IF, Flow Cyt |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti-HLA-DR Monoclonal antibody, purified [LN3]. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5 [taken from NCBI Entrez Gene (Gene ID: 3122)]. |
| Immunogen | Activated human peripheral blood mononuclear cells |
| Other Names | MHC class II antigen DRA; HLA-DRA1; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain |
| Gene, Accession # | Accession: NP_061984.2, Gene ID: 3122, UniProt: P01903 |
| Catalog # | A500-022A |
| Price | $482 |
| Order / More Info | HLA-DR Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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