RAN Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityRAN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted: rat, zebrafish, X. laevis, X. tropicalis, chicken, bovine, dog, orangutan)
Isotypen/a
Formataffinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsWB, IP, IHC
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DescriptionRabbit anti-RAN antibody, affinity purified. RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor [taken from NCBI Entrez Gene (Gene ID: 5901)].
ImmunogenBetween 166 and C-terminus
Other NamesOK/SW-cl.81; TC4; ras-related nuclear protein; RanGTPase; member RAS oncogene family; GTP-binding nuclear protein Ran; GTPase Ran; Gsp1; ARA24; androgen receptor-associated protein 24; ras-like protein TC4; guanosine triphosphatase Ran
Gene, Accession #Accession: NP_006316.1, Gene ID: 5901, UniProt: P62826
Catalog #A304-298A
Price$433
Order / More InfoRAN Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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