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Antigenic Specificity | SMAD4 |
Clone | BLR133J |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 10 µl (5+ tests) |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC, ICC, Flow Cyt |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-SMAD4 recombinant monoclonal antibody [BLR133J]. The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. SMAD4 functions in the transforming growth factor-beta signaling pathway as well as the bone morphogenetic protein signaling pathway, regulating cell proliferation, angiogenesis, and increasing blood vessel hyperpermeability. [taken from NCBI Entrez Gene (Gene ID: 4089)]. |
Immunogen | Between 1 and 50 |
Other Names | mothers against decapentaplegic homolog 4; Mothers against DPP homolog 4; SMAD, mothers against DPP homolog 4; SMAD family member 4; MYHRS; Smad4; mothers against decapentaplegic, Drosophila, homolog of, 4; MAD homolog 4; JIP; hSMAD4; DPC4; deletion target in pancreatic carcinoma 4; deleted in pancreatic carcinoma locus 4; SMAD 4; MADH4 |
Gene, Accession # | Accession: NP_005350.1, Gene ID: 4089, UniProt: Q13485 |
Catalog # | A700-133-T |
Price | $127 |
Order / More Info | SMAD4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |