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Antigenic Specificity | ZAP70 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ZAP70 antibody, affinity purified. ZAP-70 (zeta associated protein 70) is a tyrosine kinase of the Src family of tyrosine kinases. It was initially identified as a partner of the zeta chain of the CD3 complex associated to the T-cell receptor on T-lymphocytes. ZAP-70 shares homology with spleen-tyrosine kinase (Syk), a kinase involved in B-cell activation. Both ZAP-70 and Syk have been shown to be crucial to B- and T-lymphocyte development. In T-cells ZAP-70 functions to transduce the signaling cascade activated by T-cell receptor engagement and activation. |
Immunogen | Between 569 and C-terminus |
Other Names | ZAP-70; syk-related tyrosine kinase; zeta chain of T cell receptor associated protein kinase 70kDa; TZK; tyrosine-protein kinase ZAP-70; zeta-chain associated protein kinase, 70kD; STCD; SRK; IMD48; ADMIO2; 70 kDa zeta-chain associated protein; 70 kDa zeta-associated protein; zeta-chain (TCR) associated protein kinase 70kDa; STD |
Gene, Accession # | Accession: NP_001070.2, Gene ID: 7535, UniProt: P43403 |
Catalog # | A301-818A-T |
Price | $121 |
Order / More Info | ZAP70 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |