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Antigenic Specificity | TAK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: mouse, rat, bovine, orangutan) |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TAK1 antibody, affinity purified. TAK1 (TGF-beta activated kinase 1) is also called mitogen-activated protein kinase kinase kinase 7 (MAP3K7). TAK1 is a serine/threonine protein kinase that mediates signals transduced by proinflammatory cytokines such as TGF-beta, tumor necrosis factor (TNF), interleukin-1 (IL-1) and wnt family ligands. TAK1 transduces signals by stimulating a MAPK pathway that ultimately stimulates JNK (c-terminal jun kinase) and p38 MAPKs. TAK1 is also an activator of the Ikappa B kinase that leads to the activation of NFkappa-B. |
Immunogen | Between 225 and 275 |
Other Names | TAK1; TGF-beta-activated kinase 1; TGF-beta activated kinase 1; TGF1a; MEKK7; FMD2; CSCF; transforming growth factor-beta-activated kinase 1; mitogen-activated protein kinase kinase kinase 7 |
Gene, Accession # | Accession: NP_663306.1, Gene ID: 6885, UniProt: O43318 |
Catalog # | A301-915A-T |
Price | $121 |
Order / More Info | TAK1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |