Edit |   |
---|---|
Antigenic Specificity | AATF/Che-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-AATF/Che-1 antibody, affinity purified. AATF/Che-1 was identified as a protein that interacts with RNA polymerase II and is involved in the regulation of gene transcription and cell proliferation. AATF/Che-1 has been demonstrated to promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) and interfering with HDAC1's interaction with the growth inhibiting protein pRB. AATF has also been shown to function as a nuclear receptor coactivator and a repressor of apoptosis. |
Immunogen | Between 510 and C-terminus |
Other Names | protein AATF; rb-binding protein Che-1; DED; CHE-1; CHE1; BFR2; Apoptosis-antagonizing transcription factor |
Gene, Accession # | Accession: NP_036270.1, Gene ID: 26574, UniProt: Q9NY61 |
Catalog # | A301-032A-T |
Price | $121 |
Order / More Info | AATF/Che-1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |