Edit |   |
---|---|
Antigenic Specificity | SPAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-SPAK antibody, affinity purified. STE20/SPS1-related proline-alanine rich protein kinase (SPAK) is a serine/threonine kinase that is thought to function in the cellular stress response pathway. This kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. Catalytically active SPAK specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress [taken from NCBI Entrez Gene (GeneID: 27347)]. |
Immunogen | Between 425 and 475 |
Other Names | serine/threonine-protein kinase 39; ste-20-related kinase; Ste20-like protein kinase; STE20/SPS1-related proline-alanine-rich protein kinase; STE20/SPS1 homolog; small intestine SPAK-like kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); proline-alanine-rich STE20-related kinase; PASK; DCHT; SPAK |
Gene, Accession # | Accession: AAC72238.1, Gene ID: 27347, UniProt: Q9UEW8 |
Catalog # | A302-466A |
Price | $433 |
Order / More Info | SPAK Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |