TDP43 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | TDP43 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted: orangutan) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-TDP43 antibody, affinity purified. Tar DNA-binding protein 43 (TDP43) is a DNA and RNA-binding protein which regulates transcription and splicing. It is involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TDP43 may also be involved in microRNA biogenesis, apoptosis and cell division. TDP43 can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Also, TDP43 stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q13148]. |
| Immunogen | Between 175 and 225 |
| Other Names | TAR DNA-binding protein-43; TAR DNA-binding protein 43; ALS10; TDP-43 |
| Gene, Accession # | Accession: NP_031401.1, Gene ID: 23435, UniProt: Q13148 |
| Catalog # | A303-223A |
| Price | $433 |
| Order / More Info | TDP43 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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