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Antigenic Specificity | Estrogen Receptor Alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Estrogen Receptor Alpha antibody, affinity purified. The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported; these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor. |
Immunogen | Between 545 and C-terminus |
Other Names | estrogen nuclear receptor alpha; ESTRR; NR3A1; oestrogen receptor alpha; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor; nuclear receptor subfamily 3 group A member 1; ESRA; ESR; ER-alpha; Era; ER; E2 receptor alpha; estradiol receptor |
Gene, Accession # | Accession: NP_000116.2, Gene ID: 2099, UniProt: P03372 |
Catalog # | A300-498A |
Price | $433 |
Order / More Info | Estrogen Receptor Alpha Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |