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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Caspase 3 antibody, affinity purified. Caspase 3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 3 cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase 3 is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease [taken from NCBI Entrez Gene (Gene ID: 836)]. |
Immunogen | Between 1 and 50 |
Other Names | CPP32B; SREBP cleavage activity 1; SCA-1; protein Yama; procaspase3; PARP cleavage protease; CPP-32; CPP32; caspase-3; caspase 3, apoptosis-related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; CASP-3; apopain; cysteine protease CPP32 |
Gene, Accession # | Accession: NP_004337.2, Gene ID: 836, UniProt: P42574 |
Catalog # | A303-657A |
Price | $433 |
Order / More Info | Caspase 3 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |