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Antigenic Specificity | FLN29 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-FLN29 antibody, affinity purified. FLN29 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. FLN29 may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation It may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O14545]. |
Immunogen | Between 1 and 50 |
Other Names | FLN29; FLN29 gene product; Protein FLN29; TRAF-type zinc finger domain-containing protein 1 |
Gene, Accession # | Accession: NP_001137378.1, Gene ID: 10906, UniProt: O14545 |
Catalog # | A304-674A |
Price | $433 |
Order / More Info | FLN29 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |