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Antigenic Specificity | ApoE |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 1 mg |
Concentration | 1 mg/ml |
Applications | WB, ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti-Human Apo E antibody, affinity purified. Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels. |
Immunogen | Human Apolipoprotein E |
Other Names | apolipoprotein C-III; Apolipoprotein C3; ApoC-III; APOCIII; Apo-CIII |
Gene, Accession # | Accession: NP_000031.1, Gene ID: 345, UniProt: P02656 |
Catalog # | A81-118A-1MG |
Price | $307 |
Order / More Info | ApoE Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |