NHERF1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | NHERF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted: mouse, rat, chicken, bovine) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 10 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-NHERF1 antibody, affinity purified. NHERF1 (sodium-hydrogen exchanger regulatory factor 1) is a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer [taken from NCBI Entrez Gene (Gene ID: 9368)]. |
| Immunogen | Between 308 and C-terminus |
| Other Names | Na+/H+ exchange regulatory co-factor; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; Sodium-hydrogen exchanger regulatory factor 1; regulatory cofactor of Na(+)/H(+) exchanger; NPHLOP2; NHERF; NHERF1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Ezrin-radixin-moesin-binding phosphoprotein 50; ezrin-radixin-moesin binding phosphoprotein-50; EBP50; NHERF-1 |
| Gene, Accession # | Accession: NP_004243.1, Gene ID: 9368, UniProt: O14745 |
| Catalog # | A302-975A-T |
| Price | $121 |
| Order / More Info | NHERF1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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