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Antigenic Specificity | PHAX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PHAX antibody, affinity purified. Phosphorylated adapter RNA export protein (PHAX) is a phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. PHAX also plays a role in the biogenesis of U3 small nucleolar RNA (snoRNA). It is involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H814]. |
Immunogen | Between 344 and C-terminus |
Other Names | phosphorylated adapter RNA export protein; RNA U small nuclear RNA export adapter protein; RNA U, small nuclear RNA export adapter (phosphorylation regulated); RNA U, small nuclear RNA export adaptor (phosphorylation regulated); RNUXA |
Gene, Accession # | Accession: NP_115553.2, Gene ID: 51808, UniProt: Q9H814 |
Catalog # | A303-916A |
Price | $433 |
Order / More Info | PHAX Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |