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Antigenic Specificity | Chk1, Phospho (S317) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Phospho Chk1 (S317) antibody, affinity purified. Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. |
Immunogen | Surrounding serine 317 |
Other Names | cell cycle checkpoint kinase; serine/threonine-protein kinase Chk1; Chk1-S; CHK1 checkpoint homolog; CHK1; Checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1 |
Gene, Accession # | Accession: NP_001265.1, Gene ID: 1111, UniProt: O14757 |
Catalog # | A304-673A |
Price | $479 |
Order / More Info | Chk1, Phospho (S317) Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |