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Antigenic Specificity | Fibrillarin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Fibrillarin antibody, affinity purified. Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. Fibrillarin contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin [taken from NCBI Entrez Gene (Gene ID: 2091)]. |
Immunogen | Between 271 and C-terminus |
Other Names | RNA, U3 small nucleolar interacting protein 1; RNU3IP1; Nop1; histone-glutamine methyltransferase; FIB; 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; rRNA 2'-O-methyltransferase fibrillarin; FLRN |
Gene, Accession # | Accession: NP_001427.2, Gene ID: 2091, UniProt: P22087 |
Catalog # | A303-891A |
Price | $433 |
Order / More Info | Fibrillarin Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |