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Antigenic Specificity | FBP17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: rat) |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-FBP17 antibody, affinity purified. FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96RU3]. |
Immunogen | Between 350 and 400 |
Other Names | FBP17; formin-binding protein 1; formin-binding protein 17; hFBP17 |
Gene, Accession # | Accession: NP_055848.1, Gene ID: 23048, UniProt: Q96RU3 |
Catalog # | A302-790A-T |
Price | $121 |
Order / More Info | FBP17 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |