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Antigenic Specificity | ARID4B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 100 µg/ml |
Applications | IHC, IHC-IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ARID4B IHC antibody, affinity purified. ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies. |
Immunogen | Between 125 and 175 |
Other Names | breast cancer-associated antigen BRCAA1; sin3-associated polypeptide p180; SIN3A-associated protein 180; SAP180; retinoblastoma-binding protein 1-like 1; RBP1L1; RBBP1L1; Rb-binding protein homolog; breast carcinoma-associated antigen; breast cancer-associated antigen 1; BRCAA1; BCAA; AT-rich interactive domain-containing protein 4B; AT rich interactive domain 4B (RBP1-like); ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; histone deacetylase complex subunit SAP180 |
Gene, Accession # | Accession: NP_057458.4, Gene ID: 51742, UniProt: Q4LE39 |
Catalog # | IHC-00657-T |
Price | $121 |
Order / More Info | ARID4B Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |