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Antigenic Specificity | TNF Receptor II |
Clone | 80M2 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | purified |
Size | 50 µg |
Concentration | 100 µg/ml |
Applications | ELISA, FACS, Functional Assay, ICC/IF, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti-TNF Receptor II monoclonal antibody [80M2]. The monoclonal antibody 80M2 recognizes the extracellular part of membrane-bound TNF-RII as well as the soluble form of TNF-RII which is generated by proteolytic cleavage of the extracellular domain. The soluble form can still bind TNF-alpha with high affinity and functions as a TNF-alpha antagonist. The antibody is a non-agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII. |
Immunogen | n/a |
Other Names | CD120b,TBPII,TNF receptor superfamily member 1B,TNFBR,TNFR1B,TNFR2,TNFR75,TNFR80,TNFRII,TNFRSF1B,p75,p75TNFR,TNF receptor II |
Gene, Accession # | Gene ID: 7133, UniProt: P20333 |
Catalog # | GTX54424 |
Price | $399 |
Order / More Info | TNF Receptor II Antibody from GENETEX INC. |
Product Specific References | PubMed: 30352759 |