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Antigenic Specificity | Mouse PD-1 |
Clone | RMP1-14 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | Western Blot, Blocking, Flow Cytometry, Functional Assays. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1. CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production. |
Immunogen | Mouse PD-1 transfected BHK cells |
Other Names | Programmed cell death protein 1, Pdcd1, CD279 |
Gene, Accession # | UniProt: Q02242 |
Catalog # | ICH1182-50mg |
Price | $3750 |
Order / More Info | Mouse PD-1 Antibody from ICHORBIO |
Product Specific References | n/a |
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