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Antigenic Specificity | Mouse CTLA-4 |
Clone | 9H10 |
Host Species | Syrian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | Protein A/G purified, low endotoxin |
Size | 25mg |
Concentration | 1.0 - 5.0 mg/ml |
Applications | Western Blot, Blocking, ELISA, Flow Cytometry. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding. |
Immunogen | Mouse CTLA-4-human IgG1 fusion protein |
Other Names | Ctla4, Cytotoxic T-lymphocyte protein 4, CD152 |
Gene, Accession # | UniProt: P09793 |
Catalog # | ICH1084UL-25mg |
Price | $1500 |
Order / More Info | Mouse CTLA-4 Antibody from ICHORBIO |
Product Specific References | n/a |
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