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Antigenic Specificity | CD52 |
Clone | YTH34.5 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | Ctox, ELISA, Flo, IHC, IHC-Fr, IHC-P, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kD, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies ;. |
Immunogen | n/a |
Other Names | CD52, Cambridge pathology 1 antigen, CD52 antigen, CD52 molecule, CDW52, He5 |
Gene, Accession # | CD52, Gene ID: 1043 |
Catalog # | LS-C188149-0.5 |
Price | $823 |
Order / More Info | CD52 Antibody from LSBio |
Product Specific References | n/a |