ACTC1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Edit | |
|---|---|
| Antigenic Specificity | ACTC1, Human |
| Clone | REAL970 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ACTC1 Antibody, anti-human, PE, REAdye_lease™. Clone REAL970 is an antibody fragment derived from the full ACTC1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL970 recognizes ACTC1, which is also known as cardiac muscle alpha actin or Alpha-cardiac actin. It is an important protein of the thin filament in cardiac sarcomeres, which play a crucial role in muscle contraction and support the pump function of the heart. It belongs to the actin family, highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in eukaryotic cells. Mutations in ACTC1 lead to dilated cardiomyopathy. ACTC1 is considered as a prognostic marker for glioma and for liver metastasis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | | | | |
| Immunogen | n/a |
| Other Names | cardiac muscle alpha actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC |
| Gene, Accession # | n/a |
| Catalog # | 130-127-358 |
| Price | $460 |
| Order / More Info | ACTC1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Olson, T. M. et al. (1998) Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. Science 280 (5364): 750-752. | Ohtaki, S. et al. (2017) ACTC1 as an invasion and prognosis marker in glioma. J Neurosurg. 126 (2): 467-475. | Ingles, J. et al. (2019) Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes. Circ Genom Precis Med 12 (2): e002460.. | Eun-Kyung, K. et al. (2019) Proteomic Analysis of Primary Colon Cancer and Synchronous Solitary Liver Metastasi. Cancer Genomics Proteomics 16 (6): 583-592. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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