CD307a (FcRL1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD307a (FcRL1), Human |
| Clone | REA440 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio Bright V423 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD307a (FcRL1) Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA440 recognizes the human CD307a antigen, a single-pass type I membrane protein which is also known as Fc receptor-like protein 1 (FcRL1) or immune receptor translocation-associated protein 5 (IRTA5). CD307a is preferentially expressed on naive and memory B cells. It has two ITAM-like motifs, an acidic glutamic acid residue in its transmembrane region, and three extracellular immunoglobulin-like domains. Ligands for CD307a have not been identified, but the presence of ITAM-like motifs suggests its potential for B cell-activation. | Additional information: Clone REA440 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | FcRL1, FcRH1, IFGP1, IRTA5 |
| Gene, Accession # | Gene ID: 115350 |
| Catalog # | 130-131-093 |
| Price | $500 |
| Order / More Info | CD307a (FcRL1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Leu, C. M. et al. (2005) FcRH1: an activation coreceptor on human B cells. Blood 105 (3): 1121-1126. | Polson, A. G. et al. (2006) Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia. Int. Immunol. 18 (9): 1363-1373. | Davis, R. S. et al. (2001) Identification of a family of Fc receptor homologs with preferential B cell expression. Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772-9777. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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