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Antigenic Specificity | TRA-1-81, Human |
Clone | REA246 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRA-1-81 Antibody, anti-human, PE, REAfinity™. Clone REA246 recognizes a carbohydrate epitope expressed on podocalyxin, which is a transmembrane sialoglycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and malignancy marker. The expression of TRA-1-81 antigen is stage-specific and is lost upon differentiation of human EC and ES cells, making it a marker of undifferentiated pluripotent ES cells. | Additional information: Clone REA246 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin |
Gene, Accession # | Gene ID: 5420 |
Catalog # | 130-123-334 |
Price | $119 |
Order / More Info | TRA-1-81, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Schopperle, W. M. et al. (2007) The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Stem Cells 25 (3): 723-730. | Sekine, K. et al. (2020) Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media. Sci Rep 10: 17937. |