CD186 (CXCR6), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD186 (CXCR6), Mouse |
| Clone | REA1193 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD186 (CXCR6) Antibody, anti-mouse, PE, REAfinity™. Clone REA1193 recognizes the mouse CD186 chemokine receptor, which is also known as Cxcr6 (receptor for the C-X-C chemokine CXCL16). CD186 is expressed by naive CD8 T cells, natural killer T cells, and a subset of memory CD4 T cells. | The chemokine CXCL16 is produced by dendritic cells (DCs) in lymphoid organ T cell zones and by cells in the splenic red pulp. It is reported, that CXCL16 plays a role in promoting interactions between DCs and CD8 T cells and in guiding T cell movements in the splenic red pulp.Furthermore, CXCL16 and CXCR6 play an essential role in the maintenance of cardiac allograft tolerance mediated by NKT cells. | Additional information: Clone REA1193 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CXC-R6, CXCR-6, CXCR6, BONZO, STRL33 |
| Gene, Accession # | Gene ID: 80901 |
| Catalog # | 130-122-754 |
| Price | $68 |
| Order / More Info | CD186 (CXCR6), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Matloubian, M. et al. (2000) A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol 1 (4): 298-304. | Jiang, X. et al. (2005) Cutting edge: critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance. J Immunol 175 (4): 2051-2055. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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