Aiolos, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Aiolos, Human |
| Clone | REA881 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Aiolos Antibody, anti-human, APC, REAfinity™. Clone REA881 recognizes the human transcription factor aiolos, also known as IKZF3. Aiolos is a member of the ikaros family of zinc-finger proteins and forms heterodimers with other ikaros family members. It plays an essential role in the control of B lymphocyte differentiation and proliferation and in the regulation of BCL2 expression. Furthermore, it is involved in controlling apoptosis in T cells in an IL-2-dependent manner. Aiolos is found in peripheral blood leukocytes, spleen, and thymus. | Additional information: Clone REA881 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IKZF3, Znfn1a3 |
| Gene, Accession # | Gene ID: 22806 |
| Catalog # | 130-114-418 |
| Price | $140 |
| Order / More Info | Aiolos, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Romero, F. et al. (1999) Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization. EMBO J. 18 (12): 3419-3430. | Caballero, R. et al. (2007) Combinatorial effects of splice variants modulate function of Aiolos. J. Cell. Sci. 120 (15): 2619-2630. | Billot, K. et al. (2010) Differential aiolos expression in human hematopoietic subpopulations. Leuk. Res. 34 (3): 289-293. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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