Edit |   |
---|---|
Antigenic Specificity | CD11a, Rat |
Clone | REA596 |
Host Species | Recombinant Human |
Reactive Species | rat |
Isotype | IgG1 |
Format | Vio Bright FITC conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11a Antibody, anti-rat, Vio® Bright FITC, REAfinity™. Clone REA596 recognizes the rat CD11a antigen, a single-pass type I membrane protein, also known as integrin α-L (ITGAL). Integrins are heterodimeric adhesion molecules comprised of α- and β-subunits that participate in immune cell interactions as well as in immune cell-extracellular matrix interactions. CD11a combines with CD18 (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. | Additional information: Clone REA596 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ITGAL, LFA-1, ITGA |
Gene, Accession # | Gene ID: 308995 |
Catalog # | 130-109-127 |
Price | $187 |
Order / More Info | CD11a, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Tamatani, T. et al. (1991) Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur. J. Immunol. 21 (3): 627-633. | Tamatani, T. et al. (1991) Molecular mechanisms underlying lymphocyte recirculation. II. Differential regulation of LFA-1 in the interaction between lymphocytes and high endothelial cells. Eur. J. Immunol. 21 (3): 855-858. |