ADAMTS13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | ADAMTS13, Human |
| Clone | REA593 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio B515 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ADAMTS13 Antibody, anti-human, Vio® B515, REAfinity™. Clone REA593 recognizes the human ADAMTS13 antigen, which is also known as von Willebrand factor-cleaving protease (VWFCP). ADAMTS13 is a disintegrin and metalloproteinase with a thrombospondin type 1 motif which splits the VWF multimers in plasma into smaller forms thereby controlling VWF-mediated platelet thrombus formation. ADAMTS13 is expressed in liver and secreted in blood. | Additional information: Clone REA593 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | ADAM-TS 13, vWF-CP, VWFCP |
| Gene, Accession # | Gene ID: 11093 |
| Catalog # | 130-129-227 |
| Price | $385 |
| Order / More Info | ADAMTS13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Akiyama, M. et al. (2009) Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor. Proc. Natl. Acad. Sci. U.S.A. 106 (46): 19274-19279. | Soejima, K. et al. (2001) A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease? J. Biochem. 130 (4): 475-480. | Furlan, M. et al. (2001) Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease. Best Pract Res Clin Haematol 14 (2): 437-454. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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