CD53, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD53, Rat |
| Clone | REA512 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD53 Antibody, anti-rat, APC, REAfinity™. Clone REA512 recognizes the rat CD53 antigen, also known as Ox-44, a 43 kDa glycoprotein and a member of the tetraspanin family, which has four transmembrane domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD53 is expressed on almost all hematopoietic cells such as B cells, monocytes, macrophages, neutrophils, und T cells, but not on erythrocytes and platelets. | Additional information: Clone REA512 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Ox-44, TSPAN25 |
| Gene, Accession # | Gene ID: 24251 |
| Catalog # | 130-107-865 |
| Price | $61 |
| Order / More Info | CD53, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tomlinson, M. G. (1993) Epitope mapping of anti-rat CD53 monoclonal antibodies. Implications for the membrane orientation of the Transmembrane 4 Superfamily. Eur. J. Immunol. 23 (1): 136-140. | Lazo, P. A. et al. (1997) Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. Cell. Immunol. 178 (2): 132-140. | Bellacosa, A. (1991) The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation. Mol. Cell. Biol. 11 (5): 2864-2872. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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