CD70, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD70, Human |
| Clone | REA292 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD70 Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA292 recognizes the human CD70 antigen, a 50 kDa type II transmembrane glycoprotein also known as CD27 ligand (CD27L) or tumor necrosis factor ligand superfamily member 7 (TNFSF7). CD70 is a member of the TNF superfamily and is expressed by activated mouse T, B, and NK lymphocytes, activated plasmacytoid dendritic cells (pDCs), chronic B cell lymphocytic leukemia, and large B cell lymphomas. It interacts with CD27, its ligand on T cells, in order to promote T-B cell cross-stimulation and co-stimulates B cell proliferation and immunoglobulin production. It also plays a role in the pDC-induced B cell differentiation. | Additional information: Clone REA292 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | CD27L, CD27LG, TNFSF7 |
| Gene, Accession # | Gene ID: 970 |
| Catalog # | 130-104-310 |
| Price | $350 |
| Order / More Info | CD70, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Bowman, M. R. et al. (1994) The cloning of CD70 and its identification as the ligand for CD27. J Immunol 152 (4): 1756-1761. | Goodwin, R. G. et al. (1993) Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Cell 73 (3): 447-456. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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