HLA-ABC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Edit | |
|---|---|
| Antigenic Specificity | HLA-ABC, Human |
| Clone | REAL286 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HLA-ABC Antibody, anti-human, APC, REAdye_lease™. Clone REAL286 is an antibody fragment derived from the full HLA-ABC antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL286 recognizes a monomorphic epitope on MHC (human major histocompatibility complex) class I molecules, HLA A, B, and C. MHC class I molecules are expressed by all human nucleated cells and are involved in presentation of peptide ligands on the cell surface for recognition by cytotoxic T cells. HLA-ABC plays an deciding role in cell-mediated immune response and tumor surveillance. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | HLA-A, HLA-B, HLA-C, AS, SPDA1, D6S204, HLA-JY3, HLC-C, PSORS |
| Gene, Accession # | n/a |
| Catalog # | 130-121-328 |
| Price | $490 |
| Order / More Info | HLA-ABC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Melsted, W. N. et al. (2017) HLA class Ia and Ib molecules and FOXP3+ TILs in relation to the prognosis of malignant melanoma patients. Clin. Immunol. 183: 191-197. | Chaganty, B. K. et al. (2015) Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion. Oncoimmunology 5 (4): e1100790. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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