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Antigenic Specificity | CD107a (LAMP-1), Human |
Clone | REAL653 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | allophycocyanin (APC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD107a (LAMP-1) Antibody, anti-human, APC, REAdye_lease™. Clone REAL653 is an antibody fragment derived from the full CD107a (LAMP-1) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL565 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110-140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8+ T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogen | n/a |
Other Names | LAMP-1, LAMPA, LGP120, LAMP1 |
Gene, Accession # | n/a |
Catalog # | 130-126-203 |
Price | $420 |
Order / More Info | CD107a (LAMP-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Sarafian, V. S. et al. (2018) Purification and characterization of human lysosomal membrane glycoproteins. APMIS 268 (1): 657-662. | Betts, M. R. et al. (2003) Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J. Immunol. Methods 281: 65-78. | Mane, S. M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 268 (1): 360-378. |