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Antigenic Specificity | CD45, Human |
Clone | REA747 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | VioGreen conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 Antibody, anti-human, VioGreen™, REAfinity™. Clone REA747 recognizes the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family, also known as the leukocyte common antigen (LCA). The CD45 molecule is a type I transmembrane protein which is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 is expressed in different isoforms (CD45RA, CD45RB, CD45RC, CD45RAB, CD45RAC, CD45RBC, CD45RO, CD45R (ABC)) depending on the differentiation status of the cell. The CD45 antibody recognizes a common epitope of all CD45 isoforms. | Additional information: Clone REA747 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Ptprc, GP180, L-CA, LY5, T200 |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 130-110-638 |
Price | $385 |
Order / More Info | CD45, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Ralph, S. J. et al. (1987) Structural variants of human T200 glycoprotein (leukocyte-common antigen). EMBO J. 6 (5): 1251-1257. | Vykoukal, J. et al. (2008) Enrichment of putative stem cells from adipose tissue using dielectrophoretic field-flow fractionation. Lab Chip 8 (8): 1386-1393. | Kurian, L. et al. (2013) Conversion of human fibroblasts to angioblast-like progenitor cells. Nat. Methods 10 (1): 77-83. |