CD107a (LAMP-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD107a (LAMP-1), Human |
| Clone | REA792 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD107a (LAMP-1) Antibody, anti-human, APC, REAfinity™. Clone REA792 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110-140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8+ T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells. | Additional information: Clone REA792 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | LAMP-1, LAMPA, LGP120, LAMP1 |
| Gene, Accession # | Gene ID: 3916 |
| Catalog # | 130-112-000 |
| Price | $142 |
| Order / More Info | CD107a (LAMP-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Fukuda, M. et al. (1988) Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences. J. Biol. Chem. 263 (35): 18920-18928. | Mane, S. M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 268 (1): 360-378. | Betts, M. R. et al. (2003) Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J. Immunol. Methods 281: 65-78. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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