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Antigenic Specificity | CD91, Human |
Clone | REA709 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD91 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA709 recognizes the human CD91 antigen, also known as low density lipoprotein receptor-related protein 1 (LRP1), alpha-2-macroglobulin receptor (A2MR), or apolipoprotein E receptor (APOER). CD91 is a type 1 transmembrane protein receptor protein which is located in the plasma membrane of cells involved in receptor-mediated endocytosis. Furthermore, CD91 plays a role in lipoprotein metabolism and cell motility, and different diseases, such as neurodegenerative diseases, atherosclerosis, and cancer. CD91 is mainly expressed in liver, brain, and lung. | Additional information: Clone REA709 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | LRP-1, A2MR, APOER |
Gene, Accession # | Gene ID: 4035 |
Catalog # | 130-128-377 |
Price | $482 |
Order / More Info | CD91, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Herz, J. et al. (1988) Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7 (13): 4119-4127. | Lillis, A. P. et al. (2005) Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability. J. Thromb. Haemost. 3 (8): 1884-1993. | Etique, N. et al. (2013) LRP-1: a checkpoint for the extracellular matrix proteolysis. Biomed Res Int: 152-163. |