CD229 (Ly-9), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD229 (Ly-9), Human |
| Clone | Hly9.1.25 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1κ |
| Format | biotin conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD229 (Ly-9) Antibody, anti-human, Biotin. Clone Hly9.1.25 reacts with CD229, a type I transmembrane glycoprotein belonging to the CD150 subfamily of leukocyte receptors of the Ig superfamily. CD229 has four extracellular Ig domains and a cytoplasmic domain containing two copies of the tyrosine-based motif (T-I/V-Y-x-x-V/I). Via this unique motif, CD229 interacts with SH2-binding phosphatases and the adapter molecules SAP, EAT-2, and Grb2. Expression of CD229 is found on T cells, B cells, NK cells, and thymocytes. CD229 interacts homophilically via its N-terminal V-like domain and is involved in enhancing T cell activation and T?2 polarization. |
| Immunogen | n/a |
| Other Names | Ly-9, SLAMF3, hly9, mLY9 |
| Gene, Accession # | Gene ID: 4063 |
| Catalog # | 130-100-032 |
| Price | $264 |
| Order / More Info | CD229 (Ly-9), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Martin, M. et al. (2005) Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. J Immunol 174: 5977-5986. | Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J Immunol 174 (11): 7033-7042. | Romero, X. et al. (2004) Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 64 (2): 132-144. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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