IL-17F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IL-17F, Mouse |
| Clone | REA666 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-17F Antibody, anti-mouse, FITC, REAfinity™. Clone REA666 recognizes the mouse interleukin 17F (IL-17F) antigen, a cytokine which is expressed by a subset of activated T cells in the lamina propria. IL-17F belongs to the IL-17 gene family, which consists of six members (IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F). All members have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape. The isoforms of IL-17F 1 and 2 (ML-1) have the highest homology to IL-17A. It has been reported, that IL-17-producing T lymphocytes comprise a distinct lineage of proinflammatory T helper cells, termed T?17 cells, that are major contributors to autoimmune disease. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of Ag-induced pulmonary inflammation. | Additional information: Clone REA666 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | Interleukin-17F |
| Gene, Accession # | Gene ID: 257630 |
| Catalog # | 130-111-859 |
| Price | $191 |
| Order / More Info | IL-17F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ivanov, I. I. et al. (2006) The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133. | Suzuki, S. et al. (2007) Expression of interleukin-17F in a mouse model of allergic asthma. Int. Arch. Allergy Immunol. 143: 89-94. | Oda, N. et al. (2005) Interleukin-17F induces pulmonary neutrophilia and amplifies antigen-induced allergic response. Am J Respir Crit Care Med. 171 (1): 12-18. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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