CD93, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD93, Mouse |
| Clone | REA298 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD93 Antibody, anti-mouse, PE, REAfinity™. Clone REA298 recognizes the mouse CD93 antigen, C-type lectin like type I transmembrane protein also known as also known as AA4.1 antigen or C1QR1. CD93 is widely expressed on hematopoietic cells such as immature dendritic cells, monocytes and macrophages, and immature B lymphocytes but also on hematopoietic progenitors and stem cells in adult bone marrow, embryonic yolk sac, and fetal liver. It mediates the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and plays a role in intercellular adhesion. CD93 is a marker for early multipotent hematopoietic precursor cells and plays a role in cell-cell interactions during hematopoietic and vascular development. It is also involved in other immunological processes such as enhancement of bacterial phagocytosis, clearance of apoptotic cells, or neutralisation of virus. | Additional information: Clone REA298 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | AA4.1, C1QR1, C1qRp, Ly68 |
| Gene, Accession # | Gene ID: 17064 |
| Catalog # | 130-128-074 |
| Price | $99 |
| Order / More Info | CD93, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Norsworthy, P. J. et al. (2004) Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol 172 (6): 3406-3414. | Petrenko, O. et al. (1999) The molecular characterization of the fetal stem cell marker AA4. Immunity 10 (6): 691-700. | Jacque, E. et al. (2015) BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J. Exp. Med. 212: 883-892. | Kim, T. S. et al. (2000) Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P). Mol. Immunol. 37 (7): 377-389. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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