Edit |   |
---|---|
Antigenic Specificity | CD62L, Human |
Clone | 145/15 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1κ |
Format | biotin conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Mass cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD62L Antibody, anti-human, Biotin. Clone 145/15 recognizes the human CD62L antigen, a 74 kDa glycoprotein and a member of the selectin family of cell surface molecules. CD62L is also known as L-selectin, LECAM-1, or LAM-1 and binds a series of glycoproteins including CD34, GlyCAM-1, and MAdCAM-1. CD62L is important for homing of naive lymphocytes via endothelial venules to peripheral lymph nodes and Peyer's patches. The CD62L antigen also contributes to the recruitment of leukocytes from the blood to areas of inflammation. Most hematopoietic cells express CD62L, including many peripheral blood B cells, T cells, monocytes, granulocytes, and some myeloid cells from bone marrow, and thymocytes. CD62L is continuously endoproteolytically cleaved from the cell surface neutrophils and lymphocytes (shedding). Proteolysis is accelerated, for example, after antigenic activation of T cells. | Always use fresh material for immunofluorescent staining of CD62L+ cells. For optimal results, the cells should not be older than 8-12 hours. Keep cells continuously cold. CD62L-expression may be rapidly lost due to shedding. |
Immunogen | n/a |
Other Names | Sell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1 |
Gene, Accession # | Gene ID: 6402 |
Catalog # | 130-113-618 |
Price | $275 |
Order / More Info | CD62L, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |