Edit |   |
---|---|
Antigenic Specificity | CBX6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CBX6 protein. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Dunham I., Nature 402:489-495(1999).The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CBX6. |
Other Names | [Chromobox protein homolog 6; CBX6] |
Gene, Accession # | [CBX6], Gene ID: 23466, NCBI: NP_001290423.1, UniProt: O95503 |
Catalog # | MBS9407239 |
Price | $200, $255 |
Order / More Info | CBX6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |