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Antigenic Specificity | FOXO3/FOXO3A |
Clone | [1B11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human FOXO3. Transcriptional activator which triggers apoptosis in the absence ofsurvival factors, including neuronal cell death upon oxidative stress.Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.Participates in post-transcriptional regulation of MYC: followingphosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34cexpression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. |
Immunogen | Immunogen: FOXO3A (AAH21224, 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Rabbit to Human FOXO3/FOXO3A; FOXO3; AF6q21; AF6q21 protein; Forkhead box O3; Forkhead box O3A; FOXO3A; FKHRL1P2; Forkhead box protein O3; FOXO2; FKHRL1] |
Gene, Accession # | [FOXO3/FOXO3A], Gene ID: 2309, NCBI: NP_001446.1, UniProt: O43524 |
Catalog # | MBS2400891 |
Price | $605 |
Order / More Info | FOXO3/FOXO3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |