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Antigenic Specificity | GAPDH (C17) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human, rabbit, chicken, dog, porcine, cat |
Isotype | n/a |
Format | unconjugated |
Size | 0.2 mg |
Concentration | 0.200 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse, rat, human, rabbit, chicken, dog, pig, and cat GAPDH by western blotting. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known for its glycolytic function of converting D-glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. In more recent studies GAPDH has been shown to be involved in membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, prostate cancer progression, programmed neuronal cell death, DNA replication, and DNA repair. GAPDH has a molecular mass of 37 kDa and its expression is upregulated in prostate, liver, and lung cancers (1-3). |
Immunogen | Immunogen: A synthetic peptide mapping near the carboxy terminus of human GAPDH. |
Other Names | [Glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; 38 kDa BFA-dependent ADP-ribosylation substrate; peptidyl-cysteine S-nitrosylase GAPDH; glyceraldehyde-3-phosphate dehydrogenase; 38 kDa BFA-dependent ADP-ribosylation substrate; BARS-38; Peptidyl-cysteine S-nitrosylase GAPDH (EC:2.6.99.-)], [Gapdh; Gapdh; Gapd; BARS-38; Gapd; GAPDH] |
Gene, Accession # | [GAPDH], Gene ID: 24383, NCBI: P04797.3, UniProt: P04797 |
Catalog # | MBS440117 |
Price | $240 |
Order / More Info | GAPDH (C17) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Meyer-Siegler K, Mauro DJ, Seal G, Wurzer J, deRiel JK, and Sirover MA. 1991. A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glcyeraldehyde-3-phosphate dehydrogenase. PNAS USA 88: 8460-8464.2.Rondinelli RH, Epner DE, and Tricoli JV. 1997. Increased glyceraldehydes-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer. Prostate Cancer Prostatic Dis. 2: 66-72.3.Tarbe N, Evtimova V, Burtscher H, Jarsch M, Alves F, and Weidle UH. 2001. Transcriptional profiling of cell lines derived from an orthotopic pancreatic tumor model reveals metastasis-associated genes. Anticancer Res. 5: 3221-3228. |