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Antigenic Specificity | IL27A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL27A antibody detects endogenous levels of total IL27A. Description: Cytokine with pro-and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to b |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Secreted. Does not seem to be secreted without coexpression of EBI3. Tissue Specificity: Expressed in monocytes and in placenta. |
Other Names | [EBI3; IL 27; IL 27 p28 subunit; IL 27A; IL 30; IL-27 subunit alpha; IL-27-A; IL27; IL27-A; IL27A; IL27A_HUMAN; IL27p28; IL30; Interleukin 27; Interleukin 27 subunit alpha; Interleukin 27, 28-KD subunit; Interleukin 30; Interleukin-27 subunit alpha; p28] |
Gene, Accession # | [IL27A], Gene ID: 246778, NCBI: NP_663634.2, UniProt: Q8NEV9 |
Catalog # | MBS9604211 |
Price | $240, $280 |
Order / More Info | IL27A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |